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Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior.Families and caregivers should be advised of the need for close observation and communication with the prescriber.The main purpose of this is to help my anxiety/depression but the sleep inducing effect is also very welcome.I may actually ask to stay on a lower dose for this purpose alone, not too sure yet.It has also been shown to improve the percentage of time in bed spent asleep, decrease nighttime awakenings and increase total time spent asleep (Winokur et al., 2000, Schittecatte et al., 2003).Taking mirtazapine for sleep People with depression are often seen to experience increased sleep (Aslan et al., 2002) whilst still having a beneficial impact on sleep continuity and duration due to its anti-histaminergic effects.A 2012 review focused on antidepressants and sleep found that in many people with sleep disorders caused by depression, mirtazapine reduces the time it takes to fall asleep and increases the quality of sleep, but that in some people it can disturb sleep, causing restless leg syndrome in 8 to 28% of people, and in rare cases causes REM sleep behavior disorder.In 2010 NICE published a guideline for treating depression that included a review of antidepressants.

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Alongside these, it may be prescribed ‘off-label’ to people experiencing prolonged periods of poor sleep. Research has shown that Mirtazapine, taken at bedtime, to have a positive impact on insomnia symptoms in people with clinical depression.

I was prescribed 30mg tablets to be taken whole right before bed, but after reading up more on the drug, I discovered that lower doses generally produce the most sedation.

After doing a bit of research and speaking to my doctor, we both decided that Avanza (mirtazapine) might be my best option--here's how it went.

-Very slight visual distortion, although (unfortunately) no hallucinations. -Vivid dreams although not as vivid as I expected from reading the experiences of others. Tonight I'm going to try a quarter of a pill (about 7.5 mg) to gauge the effect.

-Mild reduction of anxiety and feeling of calm--although not really euphoric. If this works, I may do a quarter for a couple of weeks, then a half for a couple of weeks before I move up to a full pill every night.




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